Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.34 |
| ▸ | EIF4H | Q15056 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27363938 | 0.88 | GAA (0.36) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| SCHEMBL8657477 | 0.88 | TDP1 (0.37) | ALDH1A1MAPTTDP1NPC1LMNA | |
| Ammonia Solution, Strong SCHEMBL27320686 | 0.87 | TDP1 (0.36) | ALDH1A1MAPTTDP1NPC1LMNA | |
| SCHEMBL27401108 | 0.85 | ALDH1A1 (0.32) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| SCHEMBL27375350 | 0.85 | HTT (0.34) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| Formanilide SCHEMBL27354436 | 0.83 | ALDH1A1 (0.35) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| SCHEMBL8654023 | 0.74 | ALDH1A1 (0.35) | ALDH1A1MAPTTDP1NPC1RAB9A | |
| SCHEMBL8657361 | 0.74 | HTT (0.41) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL27527209 | 0.73 | MAPT (0.32) | ALDH1A1MAPTNPC1RAB9ALMNA | |
| SCHEMBL8657501 | 0.73 | MAPT (0.35) | ALDH1A1MAPTTDP1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1053065-A | AZAOXINDOLE DERIVATIVES | PFIZER (US) | 1991-07-17 | — | — | CN | disclosed |