Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN11 | Q06124 | 2/20 | 0.48 |
| ▸ | CDC7 | O00311 | 1/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.35 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.33 |
| ▸ | EGFR | P00533 | 1/20 | 0.33 |
| ▸ | JAK1 | P23458 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30634905 | 0.81 | PTPN11 (0.47) | PTPN11HTTHSD17B10KDM5APIK3C3 | |
| SCHEMBL26619022 | 0.81 | PTPN11 (0.47) | PTPN11HTTHSD17B10KDM5APIK3C3 | |
| SCHEMBL24073373 | 0.78 | PTPN11 (0.44) | PTPN11HTTHSD17B10PIK3C3PLK1 | |
| SCHEMBL28002669 | 0.72 | SCN10A (0.41) | PTPN11HSD17B10HDAC2HDAC3HDAC1 | |
| SCHEMBL4828173 | 0.71 | PTPN11 (0.48) | PTPN11PIK3C3PLK1CFTRPRKCI | |
| SCHEMBL24073025 | 0.71 | PTPN11 (0.44) | PTPN11HSD17B10PLK1HDAC2HDAC8 | |
| SCHEMBL7458267 | 0.68 | MAPT (0.38) | PTPN11HTTHSD17B10PLK1HDAC2 | |
| SCHEMBL2067728 | 0.68 | PTPN11 (0.41) | PTPN11CDC7DBF4HTTKDM5A | |
| SCHEMBL28052540 | 0.67 | YTHDC1 (0.37) | CDC7DBF4KDM5APLK1HDAC2 | |
| SCHEMBL2061352 | 0.67 | CD44 (0.43) | HSD17B10PLK1HDAC8HDAC6EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024064316-A1 | COMPOUNDS AND COMPOSITIONS AS SMARCA2/4 INHIBITORS AND USES THEREOF | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2024-03-28 | — | — | WO | disclosed |