SCHEMBL27368056

SCHEMBL27368056

CCC12CCCCC1N(C)CC2

nearest known ligand 0.34

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SLC6A9 P48067 5/20 0.34
ALDH1A1 P00352 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
GAA P10253 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10735216 0.94 SLC6A9 (0.33) SLC6A9ALDH1A1L3MBTL1
SCHEMBL15712729 0.89 SLC6A9 (0.32) SLC6A9
SCHEMBL26945355 0.86 SLC6A9 (0.33) SLC6A9
SCHEMBL24697527 0.86 SLC6A9 (0.33) SLC6A9
SCHEMBL22970038 0.84 SLC6A9 (0.33) SLC6A9
SCHEMBL30782226 0.83 ALDH1A1 (0.37) SLC6A9ALDH1A1L3MBTL1GAA
SCHEMBL27368017 0.79 GAA (0.30) GAA
SCHEMBL23980027 0.74
SCHEMBL27368000 0.73 SLC6A9 (0.34) SLC6A9
SCHEMBL24578054 0.73

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024054926-A1 KRAS G12D INHIBITORS BRISTOL-MYERS SQUIBB COMPANY (US) 2024-03-14 WO disclosed