Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | TAS1R3 | Q7RTX0 | 15/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 15/20 | 0.40 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.34 |
| ▸ | GPR88 | Q9GZN0 | 1/20 | 0.32 |
| ▸ | DPP4 | P27487 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14521585 | 0.87 | TAS1R3 (0.47) | TAS1R3TAS1R1HDAC7HDAC8HDAC6 | |
| SCHEMBL14268998 | 0.85 | TAS1R3 (0.40) | TSHRTAS1R3TAS1R1HDAC7HDAC8 | |
| SCHEMBL20146285 | 0.79 | TAS1R3 (0.44) | TAS1R3TAS1R1HDAC7HDAC8HDAC6 | |
| SCHEMBL12156779 | 0.74 | DPP7 (0.41) | DPP4DPP8DPP9DPP7 | |
| SCHEMBL7990837 | 0.74 | CYP3A4 (0.43) | TSHR | |
| SCHEMBL825584 | 0.72 | TDP1 (0.44) | — | |
| SCHEMBL24028928 | 0.72 | PLA2G2C (0.49) | — | |
| SCHEMBL26637843 | 0.70 | TAS1R3 (0.41) | TAS1R3TAS1R1 | |
| SCHEMBL25839087 | 0.70 | CYP3A4 (0.36) | GPR88 | |
| SCHEMBL8847890 | 0.70 | ALDH1A1 (0.46) | TAS1R3TAS1R1HDAC7HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024038282-A1 | 2-AZA- AND 2-OXABICYCLO[2.1.1]HEXANE DERIVATIVES AS FACTOR XIIA ENZYME INHIBITORS | KALVISTA PHARMACEUTICALS LIMITED (GB) | 2024-02-22 | — | — | WO | disclosed |