Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | PSIP1 | O75475 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | RPS6KA2 | Q15349 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7474470 | 0.80 | CYP1A2 (0.46) | CYP1A2POLBTSHRMEN1KMT2A | |
| SCHEMBL12447538 | 0.77 | CYP1A2 (0.55) | CYP1A2POLBMAPTMEN1KMT2A | |
| SCHEMBL11400838 | 0.75 | MAPT (0.55) | POLBTSHRMAPTMEN1KMT2A | |
| SCHEMBL29403764 | 0.74 | MEN1 (0.43) | CYP1A2POLBTSHRMAPTMEN1 | |
| SCHEMBL22552399 | 0.74 | MEN1 (0.43) | CYP1A2POLBTSHRMAPTMEN1 | |
| SCHEMBL133402 | 0.73 | CYP1A2 (0.71) | CYP1A2POLBTSHRMAPTMEN1 | |
| SCHEMBL3259551 | 0.71 | CYP1A2 (1.00) | CYP1A2MAPTMEN1KMT2ACTDSP1 | |
| Hydrochloric Acid SCHEMBL5138493 | 0.69 | CYP1A2 (0.96) | CYP1A2MAPTMEN1KMT2ACTDSP1 | |
| SCHEMBL9184880 | 0.69 | CYP1A2 (0.60) | CYP1A2POLBMAPTMEN1KMT2A | |
| SCHEMBL9306130 | 0.68 | MEN1 (0.66) | CYP1A2MEN1KMT2ACTDSP1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1067052-A | The diaminophthalimides and the analogue thereof that replace | CIBA GEIGY AG (CH) | 1992-12-16 | — | — | CN | disclosed |