Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.66 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.66 |
| ▸ | SCN2A | Q99250 | 2/20 | 0.54 |
| ▸ | AR | P10275 | 1/20 | 0.47 |
| ▸ | MYC | P01106 | 1/20 | 0.45 |
| ▸ | MAX | P61244 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | HTR7 | P34969 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.41 |
| ▸ | NR1H3 | Q13133 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | ACHE | P22303 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9304659 | 0.88 | MEN1 (0.52) | MEN1KMT2ACTDSP1SCN2AAR | |
| SCHEMBL9303944 | 0.85 | MEN1 (0.49) | MEN1KMT2ACTDSP1SCN2AAR | |
| SCHEMBL6757490 | 0.83 | MAPT (0.52) | MEN1KMT2ACTDSP1SCN2AAR | |
| SCHEMBL9305057 | 0.83 | MEN1 (0.62) | MEN1KMT2ACTDSP1SCN2AAR | |
| SCHEMBL11862182 | 0.79 | MEN1 (1.00) | MEN1KMT2ACTDSP1SCN2ACYP1A2 | |
| SCHEMBL9282551 | 0.78 | ALDH1A1 (0.52) | MEN1KMT2ASCN2AARMYC | |
| SCHEMBL29211172 | 0.78 | MYC (0.49) | MEN1KMT2ASCN2AMYCMAX | |
| SCHEMBL28240316 | 0.74 | ALDH1A1 (0.58) | MEN1KMT2ASCN2AHTR7ALDH1A1 | |
| SCHEMBL17289272 | 0.74 | ALDH1A1 (0.59) | MEN1KMT2AMYCMAXALDH1A1 | |
| SCHEMBL17796945 | 0.74 | ALDH1A1 (0.59) | MEN1KMT2AMYCMAXALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0546113-A1 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-06-16 | — | — | EP | claimed |
| WO-1992003417-A2 | NONLINEAR OPTICAL MATERIALS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-03-05 | — | — | WO | claimed |
| US-5312565-A | Nonlinear optical materials | E. I. DUPONT DE NEMOURS AND COMPANY (US) | 1994-05-17 | — | — | US | disclosed |