Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.61 |
| ▸ | PKM | P14618 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27372048 | 0.86 | ALDH1A1 (0.57) | ALDH1A1PKMNPC1LMNARAB9A | |
| SCHEMBL8478091 | 0.83 | ALDH1A1 (0.64) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL19604966 | 0.79 | ALDH1A1 (0.61) | ALDH1A1PKMNPC1LMNARAB9A | |
| SCHEMBL20432018 | 0.78 | CYP2C19 (0.56) | ALDH1A1NPC1RAB9AHPGDMAPT | |
| SCHEMBL15514376 | 0.78 | ALDH1A1 (0.65) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL11197686 | 0.78 | ALDH1A1 (0.76) | ALDH1A1PKMNPC1LMNARAB9A | |
| SCHEMBL885045 | 0.78 | SMN1; SMN2 (0.69) | ALDH1A1PKMNPC1RAB9AHPGD | |
| SCHEMBL24663798 | 0.78 | ALDH1A1 (0.51) | ALDH1A1PKMNPC1LMNARAB9A | |
| SCHEMBL14757471 | 0.77 | ALDH1A1 (0.59) | ALDH1A1PKMNPC1LMNARAB9A | |
| SCHEMBL24347533 | 0.77 | ALOX12 (0.52) | ALDH1A1PKMLMNAHPGDGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024097228-A1 | COMPOUNDS TARGETING CDK11 AND METHODS OF USING THE SAME | MELIORA THERAPEUTICS, INC. (US) | 2024-05-10 | — | — | WO | disclosed |