SCHEMBL27369540

SCHEMBL27369540

c1ccc2c(c1)cc[n+]1ccc3ccccc3c21

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.48
HSD17B10 Q99714 3/20 0.48
CYP2A6 P11509 3/20 0.48
TSHR P16473 2/20 0.48
TDP1 Q9NUW8 1/20 0.48
HPRT1 P00492 1/20 0.43
HIF1A Q16665 1/20 0.40
CYP1B1 Q16678 1/20 0.40
CYP1A2 P05177 3/20 0.39
CYP2C9 P11712 1/20 0.39
CYP2C19 P33261 1/20 0.39
CYP3A4 P08684 1/20 0.39
HPGD P15428 1/20 0.39
KEAP1 Q14145 1/20 0.39
POLB P06746 1/20 0.38
CHAT P28329 1/20 0.37
KDM4E B2RXH2 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26040175 0.82 CYP2A6 (0.48) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL610868 0.73 ALDH1A1 (0.42) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL669216 0.72 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Methane SCHEMBL11666193 0.72 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL669217 0.72 ALDH1A1 (0.40) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL6684284 0.70 ALDH1A1 (0.50) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Phenanthrene SCHEMBL2087874 0.70 CYP2A6 (0.92) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Phenanthrene SCHEMBL6281749 0.70 CYP2A6 (0.92) ALDH1A1HSD17B10CYP2A6TSHRTDP1
SCHEMBL22310963 0.67 TDP1 (0.52) ALDH1A1HSD17B10CYP2A6TSHRTDP1
Phenanthrene SCHEMBL7643 0.66 CYP2A6 (1.00) ALDH1A1HSD17B10CYP2A6TSHRTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2024049159-A1 NOVEL COMPOUND AND ORGANIC LIGHT EMITTING DEVICE USING SAME 주식회사 엘지화학 2024-03-07 WO disclosed