Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCAF1 | Q9Y4B6 | 16/20 | 0.65 |
| ▸ | CTSA | P10619 | 3/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27369904 | 0.79 | DCAF1 (0.51) | DCAF1CTSAMAPK1 | |
| SCHEMBL27369855 | 0.79 | DCAF1 (0.50) | DCAF1CTSAMAPK1 | |
| SCHEMBL26795041 | 0.77 | DCAF1 (0.66) | DCAF1CTSAMAPK1 | |
| SCHEMBL27369934 | 0.76 | DCAF1 (0.48) | DCAF1CTSAMAPK1 | |
| SCHEMBL26795044 | 0.76 | DCAF1 (0.65) | DCAF1CTSAMAPK1 | |
| SCHEMBL27369938 | 0.76 | MAPK1 (0.42) | DCAF1CTSAMAPK1 | |
| SCHEMBL27278325 | 0.75 | DCAF1 (0.56) | DCAF1CTSAMAPK1 | |
| SCHEMBL27278324 | 0.75 | DCAF1 (0.63) | DCAF1CTSAMAPK1 | |
| SCHEMBL27369820 | 0.75 | DCAF1 (0.63) | DCAF1CTSAMAPK1 | |
| SCHEMBL35212428 | 0.71 | DCAF1 (0.43) | DCAF1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024092011-A1 | IRAK DEGRADERS AND USES THEREOF | KYMERA THERAPEUTICS, INC. (US) | 2024-05-02 | — | — | WO | disclosed |