Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 8/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20234908 | 0.93 | KDM4E (0.49) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL12449626 | 0.92 | SIGMAR1 (0.49) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL12516 | 0.92 | SIGMAR1 (0.49) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL20231628 | 0.92 | HRH3 (0.50) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL20231633 | 0.90 | KDM4E (0.48) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL12720 | 0.88 | ALDH1A1 (0.48) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL12449627 | 0.88 | ALDH1A1 (0.48) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL20234909 | 0.86 | KDM4E (0.55) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL20234905 | 0.85 | KDM4E (0.51) | KMT2AKDM4ETDP1RECQLHRH3 | |
| SCHEMBL20234910 | 0.84 | HRH3 (0.56) | KMT2AKDM4ETDP1RECQLHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024054954-A1 | HETEROBIFUNCTIONAL COMPOUNDS AND METHODS OF TREATING DISEASE | HALDA THERAPEUTICS OPCO, INC. (US) | 2024-03-14 | — | — | WO | disclosed |