Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCAT2 | O15382 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.45 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.45 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.45 |
| ▸ | EIF4E | P06730 | 1/20 | 0.44 |
| ▸ | CLCN2 | P51788 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.41 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29940950 | 0.81 | BCAT2 (0.59) | BCAT2KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL1203519 | 0.81 | BCAT2 (0.59) | BCAT2KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL210767 | 0.80 | BCAT2 (0.74) | BCAT2KDM4EALDH1A1CSNK1A1TYRO3 | |
| SCHEMBL30514077 | 0.80 | BCAT2 (0.74) | BCAT2KDM4EALDH1A1CSNK1A1TYRO3 | |
| SCHEMBL30863833 | 0.78 | BCAT2 (0.47) | BCAT2KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL31012518 | 0.78 | BCAT2 (0.71) | BCAT2KDM4EALDH1A1CSNK1A1TYRO3 | |
| Hydrochloric Acid SCHEMBL16463881 | 0.78 | BCAT2 (0.71) | BCAT2KDM4EALDH1A1CSNK1A1TYRO3 | |
| SCHEMBL1110181 | 0.78 | BCAT2 (0.71) | BCAT2KDM4EALDH1A1CSNK1A1TYRO3 | |
| SCHEMBL3672928 | 0.77 | KDM4E (0.52) | BCAT2KMT2AATMKDM4EALDH1A1 | |
| SCHEMBL4238940 | 0.77 | KDM4E (0.52) | BCAT2KMT2AATMKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1054850-C | Piperazine compounds used in therapy | WELLCOME FOUND (GB) | 2000-07-26 | — | — | CN | claimed |
| CN-1200725-A | Acylaminosalicyclic acid amide compound | BAYER AG (DE) | 1998-12-02 | — | — | CN | claimed |
| CN-1133593-A | Piperazine compounds for use in therapy | WELLCOME FOUND (GB) | 1996-10-16 | — | — | CN | claimed |
| CN-1054850-C | Piperazine compounds used in therapy | WELLCOME FOUND (GB) | 2000-07-26 | — | — | CN | disclosed |
| CN-1200725-A | Acylaminosalicyclic acid amide compound | BAYER AG (DE) | 1998-12-02 | — | — | CN | disclosed |
| CN-1133593-A | Piperazine compounds for use in therapy | WELLCOME FOUND (GB) | 1996-10-16 | — | — | CN | disclosed |