SCHEMBL4238940

SCHEMBL4238940

NC(=O)c1ccccc1-c1cc(Cl)ccc1Cl

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 3/20 0.52
RECQL P46063 1/20 0.50
BCAT2 O15382 1/20 0.50
CHRM1 P11229 1/20 0.49
ALDH1A1 P00352 5/20 0.47
GLA P06280 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 2/20 0.47
ATM Q13315 1/20 0.47
TP53 P04637 1/20 0.47
MAPK14 Q16539 1/20 0.46
NPC1 O15118 1/20 0.45
MAPT P10636 1/20 0.45
PKM P14618 1/20 0.45
HPGD P15428 1/20 0.45
NFKB1 P19838 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 1/20 0.45
NFKB2 Q00653 1/20 0.45
RELA Q04206 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3672928 0.86 KDM4E (0.52) KDM4ERECQLBCAT2ALDH1A1GLA
SCHEMBL7802742 0.84 ALDH1A1 (0.63) RECQLCHRM1ALDH1A1GAAKMT2A
SCHEMBL29940950 0.83 BCAT2 (0.59) KDM4EBCAT2ALDH1A1KMT2AATM
SCHEMBL1203519 0.83 BCAT2 (0.59) KDM4EBCAT2ALDH1A1KMT2AATM
SCHEMBL30863835 0.83 KDM4E (0.52) KDM4ERECQLBCAT2ALDH1A1GLA
SCHEMBL5110958 0.81 KDM4E (0.54) KDM4ERECQLBCAT2ALDH1A1GLA
SCHEMBL30219241 0.79 ALDH1A1 (0.65) KDM4ERECQLALDH1A1GLAGAA
SCHEMBL1086528 0.79 ALDH1A1 (0.65) KDM4ERECQLALDH1A1GLAGAA
SCHEMBL30514077 0.79 BCAT2 (0.74) KDM4ERECQLBCAT2ALDH1A1GAA
SCHEMBL210767 0.79 BCAT2 (0.74) KDM4ERECQLBCAT2ALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090011935-A1 Method of Inducing Tolerance of Plants Against Bacterioses BASF SE (DE) 2009-01-08 US claimed
EP-1996018-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2008-12-03 EP claimed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO claimed
WO-2009124920-A2 EMULSIFIABLE CONCENTRATE BASF SE (DE) 2009-10-15 WO disclosed
US-20090011935-A1 Method of Inducing Tolerance of Plants Against Bacterioses BASF SE (DE) 2009-01-08 US disclosed
EP-1996018-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2008-12-03 EP disclosed
WO-2007104658-A2 METHOD OF INDUCING TOLERANCE OF PLANTS AGAINST BACTERIOSES BASF SE (DE) 2007-09-20 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090011935-A1 Method of Inducing Tolerance of Plants Against Bacterioses BROX, CAT, SLC11A2 KDM4E 4657/4885RECQL 2085/4885BCAT2 142/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.