Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | RXRA | P19793 | 1/20 | 0.39 |
| ▸ | RXRB | P28702 | 1/20 | 0.39 |
| ▸ | RXRG | P48443 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.35 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ATR | Q13535 | 7/20 | 0.32 |
| ▸ | RET | P07949 | 5/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | APEX1 | P27695 | 1/20 | 0.30 |
| ▸ | PI4KA | P42356 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27376543 | 0.86 | RXRA (0.41) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL27371610 | 0.85 | CYP4F2 (0.38) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL27371608 | 0.83 | ALDH1A1 (0.40) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL27377479 | 0.82 | ALDH1A1 (0.38) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL27371856 | 0.82 | ATR (0.43) | ALDH1A1LMNAPOLBATR | |
| SCHEMBL27377578 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL32690886 | 0.82 | ALDH1A1 (0.39) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL27376556 | 0.80 | ALDH1A1 (0.46) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL30869155 | 0.79 | RXRA (0.37) | ALDH1A1LMNAPOLBRXRARXRB | |
| SCHEMBL27371860 | 0.78 | CYP4F2 (0.40) | ALDH1A1LMNAPOLBRXRARXRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024052701-A1 | NOVEL COMPOUNDS, COMPOSITIONS AND THERAPEUTIC USES THEREOF | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |
| WO-2024052702-A1 | NOVEL COMPOUNDS AS CK2 INHIBITORS | CAMBRIDGE ENTERPRISE LIMITED (GB) | 2024-03-14 | — | — | WO | disclosed |