Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 7/20 | 0.49 |
| ▸ | MAOA | P21397 | 4/20 | 0.44 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.40 |
| ▸ | HTR1B | P28222 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | HTR1E | P28566 | 1/20 | 0.40 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.40 |
| ▸ | HRH1 | P35367 | 1/20 | 0.40 |
| ▸ | HTR2B | P41595 | 1/20 | 0.40 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6399601 | 1.00 | CALML3 (0.49) | CALML3MAOAMAOBTMEM97SIGMAR1 | |
| SCHEMBL6401966 | 0.92 | CALML3 (0.41) | CALML3MAOAMAOBTMEM97SIGMAR1 | |
| SCHEMBL6401969 | 0.92 | CALML3 (0.41) | CALML3MAOAMAOBTMEM97SIGMAR1 | |
| SCHEMBL27373619 | 0.92 | CALML3 (0.40) | CALML3MAOAMAOBTMEM97SIGMAR1 | |
| SCHEMBL6396462 | 0.90 | MAOA (0.52) | CALML3MAOAMAOBLMNAPTGS1 | |
| SCHEMBL6398564 | 0.86 | CALML3 (0.51) | CALML3MAOAMAOBTMEM97SIGMAR1 | |
| SCHEMBL6398565 | 0.86 | CALML3 (0.51) | CALML3MAOAMAOBTMEM97SIGMAR1 | |
| SCHEMBL27371358 | 0.82 | CALML3 (0.55) | CALML3MAOAMAOBTMEM97SIGMAR1 | |
| SCHEMBL6397079 | 0.82 | CALML3 (0.55) | CALML3MAOAMAOBTMEM97SIGMAR1 | |
| SCHEMBL5327254 | 0.82 | MAOB (0.53) | CALML3MAOAMAOBLMNAPTGS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072222-C | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | UPJOHN CO (US) | 2001-10-03 | — | — | CN | disclosed |
| CN-1197457-A | Phenyloxazolidinones having a C-C bond to a 4-8 membered heterocyclic ring | UPJOHN CO (US) | 1998-10-28 | — | — | CN | disclosed |