Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CALML3 | P27482 | 6/20 | 0.41 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.39 |
| ▸ | HTR1A | P08908 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.39 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | DRD1 | P21728 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR1B | P28222 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 3/20 | 0.38 |
| ▸ | MAOA | P21397 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6401966 | 1.00 | CALML3 (0.41) | CALML3TMEM97SIGMAR1HTR1AADRA2A | |
| SCHEMBL27373619 | 0.94 | CALML3 (0.40) | CALML3TMEM97SIGMAR1HTR1AADRA2A | |
| SCHEMBL27372015 | 0.92 | CALML3 (0.49) | CALML3TMEM97SIGMAR1HTR1AADRA2A | |
| SCHEMBL6399601 | 0.92 | CALML3 (0.49) | CALML3TMEM97SIGMAR1HTR1AADRA2A | |
| SCHEMBL6396462 | 0.89 | MAOA (0.52) | CALML3F10MAOBMAOALMNA | |
| SCHEMBL6397617 | 0.83 | CALML3 (0.45) | CALML3TMEM97SIGMAR1HTR1AADRA2C | |
| SCHEMBL27364293 | 0.83 | CALML3 (0.45) | CALML3TMEM97SIGMAR1HTR1AADRA2C | |
| SCHEMBL5417793 | 0.82 | MAOB (0.53) | CALML3F10MAOBMAOALMNA | |
| SCHEMBL1498789 | 0.82 | MAOB (0.53) | CALML3F10MAOBMAOALMNA | |
| SCHEMBL7830672 | 0.81 | MAOB (0.44) | CALML3F10MAOBMAOALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050054683-A1 | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | HUTCHINSON DOUGLAS K (US) | 2005-03-10 | — | — | US | disclosed |
| CN-1072222-C | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | UPJOHN CO (US) | 2001-10-03 | — | — | CN | disclosed |
| CN-1197457-A | Phenyloxazolidinones having a C-C bond to a 4-8 membered heterocyclic ring | UPJOHN CO (US) | 1998-10-28 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050054683-A1 | Phenyloxazolidinones having a C-C bond to 4-8 membered heterocyclic rings | CBR1, NCOR1, RCOR1 | CALML3 3240/4885TMEM97 1329/4885SIGMAR1 39/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.