Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MITF | O75030 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | GLA | P06280 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 4/20 | 0.37 |
| ▸ | BCHE | P06276 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13996863 | 0.89 | KDM4E (0.39) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL5953337 | 0.89 | RAB9A (0.38) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10168658 | 0.80 | KDM4E (0.51) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL2737184 | 0.79 | KDM4E (0.42) | KDM4ERAB9AALDH1A1ACHEBCHE | |
| SCHEMBL14950829 | 0.79 | KDM4E (0.58) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10137263 | 0.76 | BCHE (0.39) | ACHEBCHE | |
| SCHEMBL19696374 | 0.75 | CHKA (0.46) | KDM4ERAB9AALDH1A1ACHEBCHE | |
| SCHEMBL12530382 | 0.72 | KDM4E (0.40) | KDM4ERAB9AALDH1A1ACHEBCHE | |
| SCHEMBL10136900 | 0.71 | KDM4E (0.80) | KDM4ERAB9ANPC1MITFALDH1A1 | |
| SCHEMBL10168651 | 0.69 | KDM4E (0.44) | KDM4ERAB9ANPC1MITFALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170184574-A1 | FLUORESCENCE METHOD FOR SENSING CHLORINATED DISACCHARIDES | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2017-06-29 | — | — | US | disclosed |
| US-8951503-B2 | Optical determination of glucose utilizing boronic acid adducts | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2015-02-10 | — | — | US | disclosed |
| US-8838195-B2 | Optical systems and methods for ratiometric measurement of blood glucose concentration | MEDTRONIC MINIMED, INC. (US) | 2014-09-16 | — | — | US | disclosed |
| US-8738107-B2 | Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement | MEDTRONIC MINIMED, INC. (US) | 2014-05-27 | — | — | US | disclosed |
| US-8498682-B2 | Optical determination of pH and glucose | GLUMETRICS, INC. (US) | 2013-07-30 | — | — | US | disclosed |
| US-8088097-B2 | Use of an equilibrium intravascular sensor to achieve tight glycemic control | GLUMETRICS, INC. (US) | 2012-01-03 | — | — | US | disclosed |
| US-20100274110-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | GluMetrics, Inc (US) | 2010-10-28 | — | — | US | disclosed |
| US-7751863-B2 | Optical determination of ph and glucose | GLUMETRICS, INC. (US) | 2010-07-06 | — | — | US | disclosed |
| US-20090177143-A1 | USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL | CITIBANK, N.A. | 2009-07-09 | — | — | US | disclosed |
| US-20090148956-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090148956-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090148344-A1 | OPTICAL DETERMINATION OF GLUCOSE UTILIZING BORONIC ACID ADDUCTS | SINGARAM BAKTHAN | 2009-06-11 | — | — | US | disclosed |
| US-20090018418-A1 | EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT | GLUMETRICS, INC. (US) | 2009-01-15 | — | — | US | disclosed |
| US-20080188725-A1 | OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION | MEDTRONIC MINIMED, INC. | 2008-08-07 | — | — | US | disclosed |
| US-20080188722-A1 | OPTICAL DETERMINATION OF PH AND GLUCOSE | MEDTRONIC MINIMED, INC. | 2008-08-07 | — | — | US | disclosed |