SCHEMBL5953337

SCHEMBL5953337

OBOc1cc(C[n+]2ccccc2)cc(C[n+]2cccc3c4ccc[n+](Cc5cc(C[n+]6ccccc6)cc(B(O)O)c5)c4ccc32)c1

nearest known ligand 0.39

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
KDM4E B2RXH2 2/20 0.38
MITF O75030 1/20 0.38
ALDH1A1 P00352 1/20 0.38
GLA P06280 1/20 0.38
GAA P10253 1/20 0.38
HPGD P15428 1/20 0.38
HTT P42858 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
ACHE P22303 3/20 0.33
LMNA P02545 1/20 0.31
BCHE P06276 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2737207 0.89 KDM4E (0.47) RAB9ANPC1KDM4EMITFALDH1A1
SCHEMBL13996863 0.79 KDM4E (0.39) RAB9ANPC1KDM4EMITFALDH1A1
SCHEMBL19194662 0.72
SCHEMBL10137077 0.71
SCHEMBL10168658 0.70 KDM4E (0.51) RAB9ANPC1KDM4EMITFALDH1A1
SCHEMBL2737184 0.70 KDM4E (0.42) RAB9AKDM4EALDH1A1ACHELMNA
SCHEMBL14950829 0.70 KDM4E (0.58) RAB9ANPC1KDM4EMITFALDH1A1
SCHEMBL10137204 0.70 BCHE (0.32) RAB9ANPC1ALDH1A1SMN1; SMN2ACHE
SCHEMBL10137258 0.69 KDM4E (0.38) RAB9AKDM4EALDH1A1ACHELMNA
SCHEMBL12249821 0.68 ENPP2 (0.41) RAB9AKDM4EALDH1A1ACHEBCHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9839378-B2 Optical systems and methods for ratiometric measurement of blood glucose concentration MEDTRONIC MINIMED, INC. (US) 2017-12-12 US disclosed
US-9693720-B2 Equilibrium non-consuming fluorescence sensor for real time intravascular glucose measurement MEDTRONIC MINIMED, INC. (US) 2017-07-04 US disclosed
US-20150080685-A1 EQUILIBRIUM NON-CONSUMING FLUORESCENCE SENSOR FOR REAL TIME INTRAVASCULAR GLUCOSE MEASUREMENT MEDTRONIC MINIMED, INC. (US) 2015-03-19 US disclosed
US-8983565-B2 Optical determination of pH and glucose MEDTRONIC MINIMED, INC. (US) 2015-03-17 US disclosed
US-8979790-B2 Use of an equilibrium sensor to monitor glucose concentration MEDTRONIC MINIMED, INC. (US) 2015-03-17 US disclosed
US-20140350364-A1 OPTICAL SYSTEMS AND METHODS FOR RATIOMETRIC MEASUREMENT OF BLOOD GLUCOSE CONCENTRATION CITIBANK, N.A. 2014-11-27 US disclosed
US-20140058225-A1 OPTICAL DETERMINATION OF PH AND GLUCOSE GLUMETRICS, INC. (US) 2014-02-27 US disclosed
US-20140018646-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL GLUMETRICS, INC. (US) 2014-01-16 US disclosed
US-20130287631-A1 MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION MEDTRONIC MINIMED, INC. 2013-10-31 US disclosed
US-8535262-B2 Use of an equilibrium intravascular sensor to achieve tight glycemic control GLUMETRICS, INC. (US) 2013-09-17 US disclosed
US-8473222-B2 Measurement devices and methods for measuring analyte concentration incorporating temperature and pH correction GLUMETRICS, INC. (US) 2013-06-25 US disclosed
US-20120116191-A1 USE OF AN EQUILIBRIUM INTRAVASCULAR SENSOR TO ACHIEVE TIGHT GLYCEMIC CONTROL GLUMETRICS, INC. (US) 2012-05-10 US disclosed
US-20110224516-A1 MEASUREMENT DEVICES AND METHODS FOR MEASURING ANALYTE CONCENTRATION INCORPORATING TEMPERATURE AND PH CORRECTION GLUMETRICS, INC. (US) 2011-09-15 US disclosed