Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 2/20 | 0.44 |
| ▸ | HTR1D | P28221 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6646448 | 0.87 | NPC1 (0.47) | ALDH1A1LMNASMN1; SMN2CSNK2A1GAA | |
| SCHEMBL6643354 | 0.87 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2CSNK2A1GAAPOLB | |
| SCHEMBL6644223 | 0.85 | ALDH1A1 (0.60) | ALDH1A1SMN1; SMN2CSNK2A1GAAPOLB | |
| SCHEMBL27372179 | 0.83 | ALDH1A1 (0.49) | ALDH1A1LMNASMN1; SMN2GAAPOLB | |
| SCHEMBL23546131 | 0.83 | HTR3A (0.50) | ALDH1A1SMN1; SMN2CSNK2A1ADRB2HTR1A | |
| SCHEMBL17559747 | 0.83 | SMN1; SMN2 (0.60) | ALDH1A1LMNASMN1; SMN2GAAPOLB | |
| SCHEMBL28504575 | 0.83 | MYC (0.56) | ALDH1A1LMNASMN1; SMN2GAAPOLB | |
| SCHEMBL9113476 | 0.83 | KDM4E (0.58) | ALDH1A1LMNASMN1; SMN2GAAPOLB | |
| SCHEMBL9282399 | 0.83 | ALDH1A1 (0.46) | ALDH1A1LMNASMN1; SMN2GAAPOLB | |
| SCHEMBL16448842 | 0.81 | HTT (0.65) | ALDH1A1LMNASMN1; SMN2CSNK2A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024105363-A1 | PYRIDONE AND PYRIMIDINONE INHIBITORS OF HEMATOPOIETIC PROGENITOR KINASE 1 | CURADEV PHARMA LTD (GB) | 2024-05-23 | — | — | WO | disclosed |