SCHEMBL27373232

SCHEMBL27373232

OCCC(O)c1ccccc1.[NaH].[NaH]

nearest known ligand 0.55

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
RIPK1 Q13546 1/20 0.55
LMNA P02545 1/20 0.54
KDM4E B2RXH2 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TRPA1 O75762 1/20 0.48
AOC3 Q16853 5/20 0.48
HTR1A P08908 1/20 0.42
BCAT2 O15382 1/20 0.42
NPC1 O15118 1/20 0.41
RAB9A P51151 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27438778 1.00 RIPK1 (0.55) RIPK1LMNAKDM4EL3MBTL1TRPA1
SCHEMBL1464020 0.98 RIPK1 (0.57) RIPK1LMNAKDM4EL3MBTL1TRPA1
SCHEMBL973028 0.98 RIPK1 (0.57) RIPK1LMNAKDM4EL3MBTL1TRPA1
SCHEMBL74830 0.98 RIPK1 (0.57) RIPK1LMNAKDM4EL3MBTL1TRPA1
SCHEMBL28036576 0.95 RIPK1 (0.55) RIPK1LMNAKDM4EL3MBTL1TRPA1
Bromide SCHEMBL4251425 0.95 RIPK1 (0.55) RIPK1LMNAKDM4EL3MBTL1TRPA1
SCHEMBL27769136 0.95 RIPK1 (0.55) RIPK1LMNAKDM4EL3MBTL1TRPA1
SCHEMBL27628749 0.95 RIPK1 (0.55) RIPK1LMNAKDM4EL3MBTL1TRPA1
SCHEMBL27721522 0.95 RIPK1 (0.55) RIPK1LMNAKDM4EL3MBTL1TRPA1
SCHEMBL27848643 0.95 RIPK1 (0.55) RIPK1LMNAKDM4EL3MBTL1TRPA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102770479-B Chloro-substituted polyetherimides having improved relative thermal index SABIC INNOVATIVE PLASTICS IP 2014-05-21 CN claimed
CN-101899064-B Preparation method of dihydric phenol di(dialkyl phenyl organic phosphate) JIANGSU YOKE TECHNOLOGY CO LTD 2013-06-12 CN claimed
CN-102770479-A Chloro-substituted polyetherimides having improved relative thermal index SABIC INNOVATIVE PLASTICS IP 2012-11-07 CN claimed
CN-1867592-B Process for fractionation/concentration to reduce the polydispersivity of polymers SABIC INNOVATIVE PLASTICS IP 2012-10-03 CN claimed
CN-100549066-C In the production of polyetherimide, reduce the novel method that ring forms GEN ELECTRIC (NL) 2009-10-14 CN claimed
CN-1871280-A Phase transfer catalytic process for the preparation of polyetherimides GEN ELECTRIC (US) 2006-11-29 CN claimed
CN-1867613-A Novel approach to reduce cyclics formation in the production of polyetherimides GEN ELECTRIC (US) 2006-11-22 CN claimed
CN-1867592-A Process for fractionation/concentration to reduce the polydispersivity of polymers GEN ELECTRIC (US) 2006-11-22 CN claimed
CN-1124301-C Manufacturing method for polycarbonate GEN ELECTRIC (US) 2003-10-15 CN claimed
CN-1107053-C Prepn. of 2,2'-di(N-methylphthalimido-4-phenoxy) propane SHANGHAI SYNTHETIC RESIN INST (CN) 2003-04-30 CN claimed
CN-1336364-A Prepn. of 2,2'-di(N-methylphthalimido-4-phenoxy) propane SHANGHAI CITY INST OF SYNTHETI (CN) 2002-02-20 CN claimed
CN-1225926-A Manufacturing method for polycarbonate GEN ELECTRIC (US) 1999-08-18 CN claimed
CN-102844353-B Polycarbonate diol, process for producing the same, and polyurethane and active energy ray-curable polymer composition each comprising the same MITSUBISHI CHEMICAL CORP. (JP) 2016-02-17 CN disclosed
CN-104955874-A Polymerization method and polymers formed therewith SCRIPPS RESEARCH INST 2015-09-30 CN disclosed
CN-101945923-B Process for purifying polyether polymers and mixtures obtained therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2015-07-29 CN disclosed
CN-104704024-A Methods of manufacture of bis(phthalimide)s and polyetherimides, and bis(phthalimide)s, and polyetherimides formed therefrom SABIC INNOVATIVE PLASTICS IP 2015-06-10 CN disclosed
CN-1182735-A Diphenolic quaternary salt, its preparational process and usage GEN ELECTRIC (US) 1998-05-27 CN disclosed
CN-1170699-A Adsorption process for organic base recovery from aqueous brine solutions GEN ELECTRIC (US) 1998-01-21 CN disclosed
CN-1121514-A Process for preparing bis (ether anhydrides) using alkylamine derived bismides having low melting temperatures GEN ELECTRIC (US) 1996-05-01 CN disclosed
CN-1113500-A A compolex stabilizer composition to improve the melt stability and color stability of polycarbonates GEN ELECTRIC (US) 1995-12-20 CN disclosed