Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1464020 | 1.00 | RIPK1 (0.57) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL74830 | 1.00 | RIPK1 (0.57) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL27373232 | 0.98 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL27438778 | 0.98 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL28036576 | 0.98 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL27628749 | 0.98 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| Water SCHEMBL27676524 | 0.98 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| Bromide SCHEMBL4251425 | 0.98 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL27721522 | 0.98 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1AOC3 | |
| SCHEMBL27769136 | 0.98 | RIPK1 (0.55) | RIPK1LMNAKDM4EL3MBTL1AOC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 84 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472293-B1 | SOLID CATALYST COMPONENT FOR POLYMERIZATION OF OLEFINS, CATALYST COMPRISING THE SAME AND USE THEREOF | CHINA PETROLEUM & CHEM CORP (CN) | 2017-04-26 | — | — | EP | claimed |
| EP-0496001-B1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-PHENYL-1,3-PROPANEDIOL | DAICEL CHEM (JP) | 1996-11-06 | — | — | EP | claimed |
| US-5356812-A | Processes for production of optically active 3-phenyl-1,3-propanediol by asymmetric assimilation | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1994-10-18 | — | — | US | claimed |
| EP-0494203-B1 | SYNTHESIS OF ARYL ALKANEDIOLS HAVING HIGH OPTICAL PURITY | EASTMAN KODAK CO (US) | 1993-12-08 | — | — | EP | claimed |
| EP-0496001-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-PHENYL-1,3-PROPANEDIOL | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-07-29 | — | — | EP | claimed |
| US-4921798-A | Synthesis of (aryl or arylalkyl)-3-hydroxy propionic acids and aryl alkanediols having high optical purity | EASTMAN KODAK COMPANY (US) | 1990-05-01 | — | — | US | claimed |
| JP-4152896-A | — | — | None | — | — | JP | disclosed |
| JP-5219984-A | — | — | None | — | — | JP | disclosed |
| JP-8126487-A | — | — | None | — | — | JP | disclosed |
| US-20190046515-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SA (CH) | 2019-02-14 | — | — | US | disclosed |
| US-10130619-B2 | Amido thiadiazole derivatives as NADPH oxidase inhibitors | GENKYOTEX SUISSE SA (CH) | 2018-11-20 | — | — | US | disclosed |
| US-20170348296-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | GENKYOTEX SUISSE SA (CH) | 2017-12-07 | — | — | US | disclosed |
| EP-2809156-B1 | ALLOSTERIC MODULATORS OF 5-HYDROXYTRYPTAMINE 2C RECEPTOR (5-HT2CR) | UNIV TEXAS (US) | 2017-05-24 | — | — | EP | disclosed |
| JP-H04152896-A | PRODUCTION OF OPTICALLY ACTIVE 3-PHENYL-1,3-PROPANEDIOL | DAICEL CHEM IND LTD | 1992-05-26 | — | — | JP | disclosed |
| US-5104899-A | Side effect reduction | SEPRACOR, INC. (US) | 1992-04-14 | — | — | US | disclosed |
| WO-1992002631-A1 | PROCESS FOR PRODUCING OPTICALLY ACTIVE 3-PHENYL-1,3-PROPANEDIOL | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 1992-02-20 | — | — | WO | disclosed |
| WO-1991004334-A1 | SYNTHESIS OF ARYL ALKANEDIOLS HAVING HIGH OPTICAL PURITY | EASTMAN KODAK COMPANY (US) | 1991-04-04 | — | — | WO | disclosed |
| WO-1991004334-A1 | SYNTHESIS OF ARYL ALKANEDIOLS HAVING HIGH OPTICAL PURITY | EASTMAN KODAK COMPANY (US) | 1991-04-04 | — | — | WO | disclosed |
| US-4921798-A | Synthesis of (aryl or arylalkyl)-3-hydroxy propionic acids and aryl alkanediols having high optical purity | EASTMAN KODAK COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
| US-4921798-A | Synthesis of (aryl or arylalkyl)-3-hydroxy propionic acids and aryl alkanediols having high optical purity | EASTMAN KODAK COMPANY (US) | 1990-05-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170348296-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | NOX1, NOX5, CYBB | RIPK1 3578/4885LMNA 4266/4885KDM4E 4240/4885 |
| US-20190046515-A1 | AMIDO THIADIAZOLE DERIVATIVES AS NADPH OXIDASE INHIBITORS | NOX1, NOX5, CYBB | RIPK1 3578/4885LMNA 4266/4885KDM4E 4240/4885 |
| US-10130619-B2 | Amido thiadiazole derivatives as NADPH oxidase inhibitors | NOX1, NOX5, CYBB | RIPK1 3578/4885LMNA 4266/4885KDM4E 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.