SCHEMBL27373602

SCHEMBL27373602

O=C(O)c1ccc(COCCCCCCBr)cc1

nearest known ligand 0.53

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.53
PLA2G4B P0C869 2/20 0.51
RXRA P19793 3/20 0.47
RXRB P28702 3/20 0.47
TP53 P04637 1/20 0.45
TSHR P16473 1/20 0.45
NR4A2 P43354 3/20 0.44
NPC1 O15118 1/20 0.44
POLB P06746 1/20 0.44
RAB9A P51151 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NR4A1 P22736 1/20 0.44
NR4A3 Q92570 1/20 0.44
FOLH1 Q04609 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27372528 1.00 ALDH1A1 (0.53) ALDH1A1PLA2G4BRXRARXRBTP53
SCHEMBL27719363 0.95 ALDH1A1 (0.54) ALDH1A1PLA2G4BRXRARXRBNR4A2
SCHEMBL27613996 0.86 NR4A2 (0.59) ALDH1A1PLA2G4BRXRARXRBTSHR
SCHEMBL9763639 0.85 RARB (0.50) ALDH1A1PLA2G4BTP53TSHR
SCHEMBL9321559 0.85 PLA2G4B (0.67) ALDH1A1PLA2G4BTP53TSHR
SCHEMBL9763327 0.85 RARB (0.46) ALDH1A1PLA2G4BTP53TSHR
SCHEMBL15153312 0.85 PLA2G4B (0.67) ALDH1A1PLA2G4BTP53TSHR
SCHEMBL27698928 0.85 PLA2G4B (0.53) ALDH1A1PLA2G4BRXRARXRBTP53
SCHEMBL27595132 0.85 ALDH1A1 (0.54) ALDH1A1PLA2G4BRXRARXRBTSHR
SCHEMBL1749669 0.83 PLA2G4B (0.65) ALDH1A1PLA2G4BTP53TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1082023-A The medicine and the novel benzoic acid derivative that contain benzoic acid derivative YAMANOUCHI PHARMA CO LTD (JP) 1994-02-16 CN disclosed