Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | MTOR | P42345 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PLA2G4B | P0C869 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763639 | 0.94 | RARB (0.50) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL1560685 | 0.92 | RARB (0.53) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL11168897 | 0.88 | ALDH1A1 (0.46) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL28767948 | 0.87 | CYP4A11 (0.47) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL8775067 | 0.86 | RARB (0.65) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL14672531 | 0.86 | RARB (0.65) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL27372528 | 0.85 | ALDH1A1 (0.53) | ALDH1A1PLA2G4BTP53TSHR | |
| SCHEMBL27373602 | 0.85 | ALDH1A1 (0.53) | ALDH1A1PLA2G4BTP53TSHR | |
| SCHEMBL9260821 | 0.84 | RARB (0.64) | RARBALDH1A1MEN1RARAMAPT | |
| SCHEMBL10866701 | 0.82 | RARB (0.63) | RARBALDH1A1MEN1RARAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4990505-A | Treating asthma, bronchitis; adrenergic stimulants | GLAXO GROUP LIMITED (GB) | 1991-02-05 | — | — | US | disclosed |