⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1831918 | 0.81 | — | — | |
| SCHEMBL10076715 | 0.73 | — | — | |
| SCHEMBL146112 | 0.73 | — | — | |
| SCHEMBL6781303 | 0.73 | — | — | |
| Bromide SCHEMBL4392605 | 0.71 | SIGMAR1 (0.39) | — | |
| Bromide SCHEMBL5157150 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL27947287 | 0.71 | — | — | |
| Ammonia Solution, Strong SCHEMBL28127265 | 0.71 | — | — | |
| SCHEMBL17187518 | 0.71 | USP2 (0.30) | — | |
| SCHEMBL13735003 | 0.70 | ALDH1A1 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0525936-A1 | Accelerator for curing epoxy resins | TEXACO CHEMICAL COMPANY (US) | 1993-02-03 | — | — | EP | claimed |
| JP-5194712-A | — | — | None | — | — | JP | disclosed |
| US-20160130275-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. | 2016-05-12 | — | — | US | disclosed |
| US-8486938-B2 | Pyrazolo[1,5-a]pyrimidines for antiviral treatment | GILEAD SCIENCES, INC. (US) | 2013-07-16 | — | — | US | disclosed |
| US-20120003215-A1 | PYRAZOLO[1,5-A]PYRIMIDINES FOR ANTIVIRAL TREATMENT | GILEAD SCIENCES, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| EP-1386908-B1 | AMINE DERIVATIVE WITH POTASSIUM CHANNEL REGULATORY FUNCTION, ITS PREPARATION AND USE | INST PHARM & TOXICOLOGY AMMS (CN) | 2010-03-03 | — | — | EP | disclosed |
| US-20100029008-A1 | POLYMERASE-INDEPENDENT ANALYSIS OF THE SEQUENCE OF POLYNUCLEOTIDES | FEBIT BIOTECH GMBH (DE) | 2010-02-04 | — | — | US | disclosed |
| US-7560473-B2 | Amine derivative with potassium channel regulatory function, its preparation and use | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES, P.L.A. (CN) | 2009-07-14 | — | — | US | disclosed |
| US-20070265446-A1 | Arylamine-substituted quinazolinone compounds useful as alpha 1A/B adrenergic receptor antagonists | CONNOLLY TERRENCE J | 2007-11-15 | — | — | US | disclosed |
| EP-0378910-B1 | Method for the preparation of imidazoles | TEXACO DEVELOPMENT CORP (US) | 1994-08-31 | — | — | EP | disclosed |
| US-5250638-A | Complexes less reactive than imidazole alone; extends pot life | TEXACO CHEMICAL COMPANY (US) | 1993-10-05 | — | — | US | disclosed |
| JP-H05194712-A | EPOXY RESIN COMPOSITION | TEXACO CHEM CO | 1993-08-03 | — | — | JP | disclosed |
| EP-0525940-A2 | Curable epoxy resin compositions | TEXACO CHEMICAL COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0525936-A1 | Accelerator for curing epoxy resins | TEXACO CHEMICAL COMPANY (US) | 1993-02-03 | — | — | EP | disclosed |
| EP-0378910-A1 | Method for the preparation of imidazoles | TEXACO DEVELOPMENT CORPORATION (US) | 1990-07-25 | — | — | EP | disclosed |
| US-4927942-A | Method for the preparation of imidazoles | TEXACO CHEMICAL CO. (US) | 1990-05-22 | — | — | US | disclosed |