Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.35 |
| ▸ | LCK | P06239 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27458947 | 0.79 | LMNA (0.39) | FFAR3LCKFYNKDM4EATM | |
| SCHEMBL8604616 | 0.78 | — | — | |
| SCHEMBL8158142 | 0.75 | — | — | |
| SCHEMBL12849304 | 0.73 | — | — | |
| SCHEMBL5309281 | 0.69 | KDM4E (0.46) | FFAR3LCKFYNKDM4EATM | |
| SCHEMBL58395 | 0.69 | — | — | |
| SCHEMBL11708907 | 0.69 | — | — | |
| SCHEMBL11708915 | 0.69 | — | — | |
| SCHEMBL29159287 | 0.69 | ALDH1A1 (0.30) | FFAR3LCKFYN | |
| SCHEMBL17771938 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2404890-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-11 | — | — | EP | disclosed |
| EP-2402300-A1 | Hydroxyl compounds and compositions for cholesterol management and related uses | Esperion Therapeutics Inc. (US) | 2012-01-04 | — | — | EP | disclosed |