Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22144017 | 0.81 | APLNR (0.34) | CYP1A2 | |
| SCHEMBL27375615 | 0.81 | APLNR (0.34) | CYP1A2 | |
| SCHEMBL16154380 | 0.79 | — | — | |
| SCHEMBL19982879 | 0.77 | KDM4E (0.36) | — | |
| SCHEMBL19508493 | 0.75 | CYP1A2 (0.31) | CYP1A2CYP2D6CTDSP1SIGMAR1 | |
| SCHEMBL17835279 | 0.74 | APLNR (0.36) | — | |
| SCHEMBL17490614 | 0.74 | APLNR (0.36) | — | |
| SCHEMBL17835280 | 0.74 | APLNR (0.36) | — | |
| SCHEMBL13537222 | 0.72 | CYP1A2 (0.34) | CYP1A2SIGMAR1 | |
| SCHEMBL2474412 | 0.71 | CYP2D6 (0.33) | CYP1A2CYP2D6CTDSP1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024084363-A1 | USE OF PATATIN-LIKE PHOSPHOLIPASE DOMAIN-CONTAINING PROTEIN 3 COMPOUNDS | PFIZER INC. (US) | 2024-04-25 | — | — | WO | disclosed |