SCHEMBL27374875

SCHEMBL27374875

FC(F)Oc1c(Br)cccc1CBr

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.33
MEN1 O00255 1/20 0.33
HTT P42858 1/20 0.33
KMT2A Q03164 1/20 0.33
MEP1B Q16820 1/20 0.31
TAAR1 Q96RJ0 1/20 0.31
CYP1A2 P05177 1/20 0.30
CYP2D6 P10635 1/20 0.30
TSHR P16473 1/20 0.30
NFKB1 P19838 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31152896 0.84 GABRA1 (0.45) IDO1MEN1HTTKMT2ATAAR1
SCHEMBL31076516 0.83 GABRA1 (0.34) IDO1MEN1KMT2ATAAR1CYP1A2
SCHEMBL1771083 0.82 MEN1 (0.36) MEN1HTTKMT2A
SCHEMBL1364220 0.75 MEN1 (0.41) IDO1MEN1KMT2ATAAR1TSHR
SCHEMBL30525679 0.75 MEN1 (0.41) IDO1MEN1KMT2ATAAR1TSHR
SCHEMBL23043168 0.75 SCN9A (0.36) MEN1HTTKMT2A
SCHEMBL5699178 0.73 SCN9A (0.33) MEN1HTTKMT2ATSHRHSD17B10
SCHEMBL5733263 0.73 ALDH1A1 (0.43) MEN1HTTKMT2ACYP1A2CYP2D6
SCHEMBL30079497 0.73 SCN9A (0.33) MEN1HTTKMT2ATSHRHSD17B10
SCHEMBL737295 0.73 MEN1 (0.32) MEN1HTTKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS INC (US) 2026-02-05 US disclosed
EP-4562016-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME Cedilla Therapeutics, Inc. (US) 2025-06-04 EP disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed
WO-2024026483-A2 CDK2 INHIBITORS AND METHODS OF USING THE SAME CEDILLA THERAPEUTICS, INC. (US) 2024-02-01 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034123-A1 CDK2 INHIBITORS AND METHODS OF USING THE SAME CDK2, CDK1, CDK20 IDO1 2935/4885MEN1 3868/4885HTT 3813/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.