Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 2/20 | 0.49 |
| ▸ | GRM4 | Q14833 | 4/20 | 0.45 |
| ▸ | ALKBH2 | Q6NS38 | 1/20 | 0.41 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.41 |
| ▸ | DRD2 | P14416 | 3/20 | 0.40 |
| ▸ | DRD4 | P21917 | 3/20 | 0.40 |
| ▸ | DRD3 | P35462 | 3/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.36 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | LOXL2 | Q9Y4K0 | 2/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.33 |
| ▸ | CYP21A2 | P08686 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31456934 | 1.00 | GRM5 (0.49) | GRM5GRM4ALKBH2EGLN1DRD2 | |
| SCHEMBL5217009 | 0.87 | GRM5 (0.58) | GRM5GRM4ALKBH2EGLN1DRD2 | |
| SCHEMBL27375741 | 0.83 | LOXL2 (0.33) | GRM5LOXL2MAOAKCNH2AOC3 | |
| SCHEMBL27374582 | 0.82 | GRM4 (0.45) | GRM4DRD2DRD4DRD3KCNH2 | |
| SCHEMBL31456940 | 0.82 | GRM4 (0.45) | GRM4DRD2DRD4DRD3KCNH2 | |
| Hydrochloric Acid SCHEMBL30751417 | 0.82 | LOXL2 (0.34) | GRM5LOXL2MAOAKCNH2AOC3 | |
| SCHEMBL3929204 | 0.79 | GRM5 (0.66) | GRM5GRM4ALKBH2EGLN1DRD2 | |
| SCHEMBL30795106 | 0.79 | GRM5 (0.66) | GRM5GRM4ALKBH2EGLN1DRD2 | |
| SCHEMBL31457020 | 0.79 | CYP17A1 (0.43) | GRM4LOXL2MAOACYP17A1CYP21A2 | |
| SCHEMBL27374758 | 0.79 | CYP17A1 (0.43) | GRM4LOXL2MAOACYP17A1CYP21A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |