SCHEMBL26465717

SCHEMBL26465717

CNCC(=O)N[C@H](C(=O)N1CCC[C@H]1C(=O)NCC(C)=O)C1CCCCC1

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
F2 P00734 5/20 0.45
PLAT P00750 1/20 0.45
PRSS1 P07477 1/20 0.45
BIRC2 Q13490 9/20 0.42
NPSR1 Q6W5P4 1/20 0.40
FKBP5 Q13451 1/20 0.40
XIAP P98170 1/20 0.40
BIRC3 Q13489 1/20 0.40
DPP4 P27487 1/20 0.38
POLB P06746 1/20 0.38
TSHR P16473 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27375418 0.84 DPP4 (0.41) F2PLATPRSS1BIRC2XIAP
SCHEMBL21307631 0.82 DPP4 (0.39) F2PLATPRSS1BIRC2XIAP
SCHEMBL18754852 0.80 DPP4 (0.43) BIRC2DPP4
SCHEMBL27437988 0.78 DPP4 (0.41) F2PLATPRSS1BIRC2DPP4
SCHEMBL17069040 0.76 P2RX7 (0.50) F2NPSR1DPP4POLBTSHR
SCHEMBL27438305 0.74 XIAP (0.59) BIRC2XIAPBIRC3
SCHEMBL23975499 0.74 TP53 (0.40) DPP4
SCHEMBL23975465 0.74 TP53 (0.40) DPP4
SCHEMBL22402905 0.73 BIRC2 (0.43) F2PLATPRSS1BIRC2FKBP5
SCHEMBL26461271 0.73 BIRC2 (0.43) F2PLATPRSS1BIRC2FKBP5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230132823-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR DBD THERAPEUTICS, LLC 2023-05-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230132823-A1 BI-FUNCTIONAL COMPOUNDS AND METHODS FOR TARGETED UBIQUITINATION OF ANDROGEN RECEPTOR AR, ADRM1, PSMA3 F2 4769/4885PLAT 4565/4885PRSS1 2863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.