Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 3/20 | 0.53 |
| ▸ | CA12 | O43570 | 2/20 | 0.53 |
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | CA9 | Q16790 | 2/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | MMP1 | P03956 | 1/20 | 0.39 |
| ▸ | MMP3 | P08254 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP14 | P50281 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7519699 | 0.84 | CA12 (0.51) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL18314658 | 0.81 | CA12 (0.56) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL28361937 | 0.80 | CA12 (0.54) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL22906848 | 0.79 | MMP2 (0.40) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL15840457 | 0.78 | EPHX1 (0.43) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL2018034 | 0.77 | LMNA (0.61) | EPHX2EPHX1NPSR1LMNAHPGD | |
| SCHEMBL26497836 | 0.77 | EPHX1 (0.40) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL13035821 | 0.75 | CA12 (0.61) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL1554349 | 0.75 | CA12 (0.61) | MMP2CA12CA1CA2CA9 | |
| SCHEMBL13195837 | 0.75 | CA12 (0.61) | MMP2CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073106-A1 | COMPOUNDS AND COMPOSITIONS USEFUL AS INHIBITORS OF TAPS | TRACT PHARMACEUTICALS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |