Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL15512248 | 0.95 | TP53 (0.65) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL320231 | 0.95 | TP53 (0.65) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL4527725 | 0.95 | TP53 (0.65) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL18761913 | 0.92 | TP53 (0.61) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL23093624 | 0.90 | TP53 (0.58) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL9580295 | 0.90 | TP53 (0.58) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL4311543 | 0.90 | TP53 (0.58) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL12505874 | 0.87 | TP53 (0.55) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL3482823 | 0.87 | TP53 (0.55) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Oxalic Acid SCHEMBL4365172 | 0.86 | LMNA (0.64) | LMNAALDH1A1OR51E2TDP1PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1190404-C | Condensation treatment method of desorption gas containing phenol compound, bisphenol A and steam | MITSUBISH KASEI K K (JP) | 2005-02-23 | — | — | CN | disclosed |
| CN-1190403-C | Crystallization device, preparation method and device for bisphenol A-phenol crystal adduct | MITSUBISH KASEI K K (JP) | 2005-02-23 | — | — | CN | disclosed |
| CN-1167659-C | Phenol purification, purification and production of bisphenol A-phenol crystal adduct, and production of bisphenol A | 三菱化学株式会社 | 2004-09-22 | — | — | CN | disclosed |
| CN-1059428-C | Process for producing high-grade bisphenol A | CHIYODA CHEM ENG CONSTRUCT CO (JP) | 2000-12-13 | — | — | CN | disclosed |
| CN-1274709-A | Crystal separating-out device of bisphenol A. phenol crystal adduct, manufacture ad device thereof | CHIYODA CHEM ENG CONSTRUCT CO (JP) | 2000-11-29 | — | — | CN | disclosed |
| CN-1254703-A | Processes for refining phenol, preparing and refining addition of bisphenol A and phenol crystal and preparing bisphenol A | CHIYODA CHEM ENG CONSTRUCT CO (JP) | 2000-05-31 | — | — | CN | disclosed |
| CN-1241557-A | Condensation processing method for desorption gas of compound containing phenol, bisphenol A and steam | CHIYODA CHEM ENG CONSTRUCT CO (JP) | 2000-01-19 | — | — | CN | disclosed |
| CN-1069961-A | Process for preparing and purifying crystalline adduct of bisphenol A and phenol, crystallization apparatus therefor, and process for producing bisphenol A | CHIYODA CHEM ENG CONSTRUCT CO (JP) | 1993-03-17 | — | — | CN | disclosed |