Known targets — ChEMBL curated mechanism
CHRM1DRD2DRD3DRD4HDAC1HDAC10HDAC11HDAC2HDAC3HDAC4HDAC5HDAC6HDAC7HDAC8HDAC9HRH1HTR2APDE3ASIGMAR1
The experimentally established mechanism targets of Lactic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.37 |
| ▸ | FYN | P06241 | 1/20 | 0.37 |
| ▸ | PDE4A | P27815 | 1/20 | 0.36 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.34 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Lactic Acid SCHEMBL4311543 | 1.00 | TP53 (0.58) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL15512248 | 0.95 | TP53 (0.65) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL4527725 | 0.95 | TP53 (0.65) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL320231 | 0.95 | TP53 (0.65) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL18761913 | 0.92 | TP53 (0.61) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Succinic Acid SCHEMBL27612941 | 0.91 | TP53 (0.48) | TP53LMNAALDH1A1OR51E2FFAR3 | |
| Lactic Acid SCHEMBL23093624 | 0.90 | TP53 (0.58) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Lactic Acid SCHEMBL27375809 | 0.90 | TP53 (0.58) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Glycerin SCHEMBL4808926 | 0.89 | LMNA (0.53) | TP53LMNAALDH1A1OR51E2TDP1 | |
| Glycerin SCHEMBL33458 | 0.89 | LMNA (0.60) | TP53LMNAALDH1A1OR51E2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-102036716-A | Cooling composition | GIVAUDAN SA | 2011-04-27 | — | — | CN | claimed |
| CN-112538246-A | Plastic master batch with metallic luster and preparation method thereof | 惠州莹光塑胶颜料有限公司 | 2021-03-23 | — | — | CN | disclosed |
| CN-102036716-B | Cooling composition | GIVAUDAN S.A. (CH) | 2016-02-10 | — | — | CN | disclosed |
| CN-102036716-A | Cooling composition | GIVAUDAN SA | 2011-04-27 | — | — | CN | disclosed |
| US-5187202-A | Cellulosic short fiber or floc and dispersant aid | FERRO CORPORATION (US) | 1993-02-16 | — | — | US | disclosed |