Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TYR | P14679 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | KAT8 | Q9H7Z6 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.38 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4017548 | 0.88 | HSP90AB1 (0.49) | HSP90AB1PPARAHTTMAPTHPGD | |
| SCHEMBL8968774 | 0.85 | TYR (0.50) | TYRKAT8PPARAALOX5 | |
| SCHEMBL9121697 | 0.85 | CYP1A2 (0.47) | TYRKAT8PPARAMAPTMEN1 | |
| SCHEMBL9814053 | 0.84 | TYR (0.49) | TYRKAT8PPARAMAPTMEN1 | |
| SCHEMBL9814064 | 0.84 | TYR (0.49) | TYRKAT8PPARAMAPTMEN1 | |
| SCHEMBL9814051 | 0.84 | TYR (0.49) | TYRKAT8PPARAMAPTMEN1 | |
| SCHEMBL7968004 | 0.81 | HTT (0.55) | KAT8PPARAHTTMAPTMEN1 | |
| SCHEMBL27711763 | 0.81 | HSP90AB1 (0.56) | HSP90AB1HTTMAPTHPGDMEN1 | |
| SCHEMBL10727033 | 0.80 | KAT8 (0.50) | KAT8PPARAHTTHPGDKDM4E | |
| SCHEMBL10975179 | 0.80 | CYP1A2 (0.48) | PPARAHTTMAPTHPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1071423-A | BICYCLIC CARBOXYLIC ACID DERIVATIVES | HOFFMANN LA ROCHE (CH) | 1993-04-28 | — | — | CN | disclosed |