Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MET | P08581 | 4/20 | 0.46 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.38 |
| ▸ | GSK3B | P49841 | 3/20 | 0.38 |
| ▸ | KIT | P10721 | 4/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | ERCC1 | P07992 | 1/20 | 0.34 |
| ▸ | ERCC4 | Q92889 | 1/20 | 0.34 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.34 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.34 |
| ▸ | ROS1 | P08922 | 1/20 | 0.34 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751109 | 1.00 | MET (0.46) | METDYRK1AGSK3BKITMAPK1 | |
| SCHEMBL27376365 | 0.95 | MET (0.47) | METDYRK1AGSK3BKITMAPK1 | |
| SCHEMBL30751108 | 0.95 | MET (0.47) | METDYRK1AGSK3BKITMAPK1 | |
| SCHEMBL21174281 | 0.92 | MET (0.50) | METKITMAPK1BTKPDPK1 | |
| SCHEMBL21174231 | 0.92 | MET (0.49) | METDYRK1AKITMAPK1BTK | |
| SCHEMBL21174064 | 0.92 | MET (0.49) | METDYRK1AKITMAPK1BTK | |
| SCHEMBL21174232 | 0.90 | MET (0.46) | METKITMAPK1BTKPDPK1 | |
| SCHEMBL30751474 | 0.89 | MET (0.47) | METDYRK1AGSK3BKITMAPK1 | |
| SCHEMBL27376359 | 0.89 | MET (0.47) | METDYRK1AGSK3BKITMAPK1 | |
| SCHEMBL21174213 | 0.89 | MET (0.46) | METKITMAPK1BTKPDPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |