Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIN2B | Q13224 | 3/20 | 0.38 |
| ▸ | MET | P08581 | 1/20 | 0.35 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30751065 | 1.00 | GRIN2B (0.38) | GRIN2BMETRIPK2ADORA3ADORA1 | |
| SCHEMBL27375170 | 0.90 | MET (0.37) | METDYRK1ASMO | |
| SCHEMBL30751355 | 0.90 | MET (0.37) | METDYRK1ASMO | |
| SCHEMBL27376866 | 0.89 | MET (0.37) | METDYRK1ASMO | |
| SCHEMBL21174368 | 0.89 | MET (0.46) | GRIN2BMETDYRK1A | |
| SCHEMBL27376555 | 0.88 | MET (0.35) | GRIN2BMETDYRK1A | |
| SCHEMBL30751076 | 0.88 | MET (0.35) | GRIN2BMETDYRK1A | |
| SCHEMBL21174334 | 0.87 | MET (0.47) | GRIN2BMETDYRK1A | |
| SCHEMBL30751050 | 0.86 | MET (0.36) | METDYRK1A | |
| SCHEMBL30751316 | 0.86 | MET (0.36) | METDYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |