Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 9/20 | 0.71 |
| ▸ | DRD4 | P21917 | 7/20 | 0.71 |
| ▸ | DRD3 | P35462 | 6/20 | 0.54 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.53 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.53 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.53 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.53 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.52 |
| ▸ | ATM | Q13315 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 2/20 | 0.52 |
| ▸ | HTR7 | P34969 | 4/20 | 0.51 |
| ▸ | DRD5 | P21918 | 3/20 | 0.51 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.47 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.47 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096608 | 0.94 | DRD2 (0.80) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9096389 | 0.87 | DRD2 (0.83) | DRD2DRD4DRD3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL9096256 | 0.86 | DRD2 (0.81) | DRD2DRD4DRD3CHRM2CHRM4 | |
| Oxalic Acid SCHEMBL27398516 | 0.85 | DRD2 (0.52) | DRD2DRD4MEN1KMT2AATM | |
| SCHEMBL9096134 | 0.83 | DRD2 (0.62) | DRD2DRD4DRD3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL9095647 | 0.81 | DRD4 (0.60) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL9096176 | 0.80 | DRD2 (0.79) | DRD2DRD4DRD3CHRM2CHRM4 | |
| SCHEMBL24270340 | 0.79 | KMT2A (0.72) | DRD2DRD4MEN1KMT2AATM | |
| SCHEMBL9096207 | 0.79 | DRD4 (0.57) | DRD2DRD4DRD3CHRM2CHRM4 | |
| Hydrochloric Acid SCHEMBL9095767 | 0.78 | DRD4 (0.56) | DRD2DRD4DRD3CHRM2CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079464-A | Treatment comprises the preparation method of the valuable indolone of illness of cholinergic function reduction and the derivative of indole dione | ASTRA AB (SE) | 1993-12-15 | — | — | CN | disclosed |