Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 2/20 | 0.52 |
| ▸ | DRD4 | P21917 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9096207 | 0.95 | DRD4 (0.57) | DRD2DRD4 | |
| SCHEMBL9095908 | 0.86 | DRD2 (0.62) | DRD2DRD4KDM4EALDH1A1KMT2A | |
| Oxalic Acid SCHEMBL27377361 | 0.85 | DRD2 (0.71) | DRD2DRD4KMT2AMEN1ATM | |
| Hydrochloric Acid SCHEMBL9095647 | 0.85 | DRD4 (0.60) | DRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9095767 | 0.83 | DRD4 (0.56) | DRD2DRD4ALDH1A1 | |
| SCHEMBL9096134 | 0.82 | DRD2 (0.62) | DRD2DRD4 | |
| SCHEMBL9096608 | 0.79 | DRD2 (0.80) | DRD2DRD4KMT2AMEN1 | |
| SCHEMBL9382409 | 0.78 | DRD2 (0.49) | DRD2DRD4KDM4EALDH1A1KMT2A | |
| SCHEMBL9096623 | 0.77 | DRD4 (0.51) | DRD2DRD4KMT2AMEN1 | |
| SCHEMBL9094905 | 0.76 | DRD4 (0.64) | DRD2DRD4KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1079464-A | Treatment comprises the preparation method of the valuable indolone of illness of cholinergic function reduction and the derivative of indole dione | ASTRA AB (SE) | 1993-12-15 | — | — | CN | disclosed |