Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 3/20 | 0.38 |
| ▸ | MET | P08581 | 2/20 | 0.37 |
| ▸ | BTK | Q06187 | 3/20 | 0.35 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.34 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.34 |
| ▸ | KIT | P10721 | 3/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | SMO | Q99835 | 1/20 | 0.32 |
| ▸ | WNT1 | P04628 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27375170 | 0.94 | MET (0.37) | NAMPTMETBTKDYRK1AKIT | |
| SCHEMBL30751355 | 0.94 | MET (0.37) | NAMPTMETBTKDYRK1AKIT | |
| SCHEMBL27376866 | 0.94 | MET (0.37) | NAMPTMETBTKDYRK1AKIT | |
| SCHEMBL30751480 | 0.92 | BTK (0.37) | NAMPTMETBTKADORA1DYRK1A | |
| SCHEMBL30751349 | 0.92 | NAMPT (0.37) | NAMPTMETBTKADORA1DYRK1A | |
| SCHEMBL30751367 | 0.92 | DYRK1A (0.37) | METBTKADORA1DYRK1AWNT1 | |
| SCHEMBL27374607 | 0.92 | DYRK1A (0.37) | METBTKADORA1DYRK1AWNT1 | |
| SCHEMBL30751384 | 0.92 | MET (0.36) | NAMPTMETBTKADORA1KIT | |
| SCHEMBL27375126 | 0.92 | MET (0.36) | NAMPTMETBTKADORA1KIT | |
| SCHEMBL30751461 | 0.92 | BTK (0.36) | METBTKDYRK1AWNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024030000-A1 | NOVEL COMPOUND AS HYPOXIA-INDUCIBLE FACTOR 1(HIF-1) INHIBITOR OR VASCULAR ENDOTHELIAL GROWTH FACTOR (VEGF) INHIBITOR, AND PHARMACEUTICAL COMPOSITION COMPRISING SAME | 주식회사 넥스트젠바이오사이언스 | 2024-02-08 | — | — | WO | disclosed |