Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FURIN | P09958 | 7/20 | 0.37 |
| ▸ | CTSL | P07711 | 1/20 | 0.36 |
| ▸ | SIRT5 | Q9NXA8 | 2/20 | 0.34 |
| ▸ | NMT2 | O60551 | 1/20 | 0.33 |
| ▸ | NMT1 | P30419 | 1/20 | 0.33 |
| ▸ | NPY4R | P50391 | 7/20 | 0.32 |
| ▸ | NPY1R | P25929 | 5/20 | 0.32 |
| ▸ | NPY2R | P49146 | 3/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 3/20 | 0.32 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.32 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21788282 | 0.90 | FURIN (0.38) | FURINSIRT5NMT2NMT1NPY4R | |
| SCHEMBL23126444 | 0.90 | FURIN (0.38) | FURINSIRT5NMT2NMT1NPY4R | |
| SCHEMBL22067692 | 0.90 | FURIN (0.38) | FURINSIRT5NMT2NMT1NPY4R | |
| SCHEMBL21788261 | 0.81 | FURIN (0.36) | FURINCTSLSIRT5NMT2NMT1 | |
| SCHEMBL23900963 | 0.81 | FURIN (0.36) | FURINSIRT5NMT2NMT1NPY4R | |
| SCHEMBL23917912 | 0.80 | FURIN (0.32) | FURINSIRT5SIRT6SIRT1 | |
| SCHEMBL23079360 | 0.80 | FURIN (0.39) | FURINSIRT5NMT2NMT1NPY1R | |
| SCHEMBL17424410 | 0.80 | SIRT5 (0.41) | FURINSIRT5NPY4RNPY1RNPY5R | |
| SCHEMBL17424365 | 0.79 | SIRT5 (0.44) | FURINCTSLSIRT5SIRT6SIRT1 | |
| SCHEMBL20803561 | 0.79 | C3AR1 (0.34) | FURINSIRT5SIRT6SIRT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024073436-A2 | COMPOSITIONS AND USES THEREOF | SOLVE THERAPEUTICS, INC. (US) | 2024-04-04 | — | — | WO | disclosed |