Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 10/20 | 0.65 |
| ▸ | OPRK1 | P41145 | 11/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 9/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.37 |
| ▸ | MRGPRX2 | Q96LB1 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12257903 | 1.00 | OPRM1 (0.65) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL12255370 | 0.89 | OPRM1 (0.51) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL12127582 | 0.83 | OPRM1 (0.42) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL15942834 | 0.83 | OPRM1 (0.42) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL12948089 | 0.80 | OPRM1 (1.00) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL13509416 | 0.79 | OPRD1 (0.54) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL12125460 | 0.78 | OPRD1 (0.66) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL12125447 | 0.78 | OPRD1 (0.66) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL13851509 | 0.78 | OPRD1 (0.66) | OPRM1OPRK1OPRD1LMNAPDE4D | |
| SCHEMBL10316209 | 0.78 | OPRD1 (0.66) | OPRM1OPRK1OPRD1LMNAPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2402037-A1 | Controlled release of phenolic opioids | Pharmacofore, Inc. (US) | 2012-01-04 | — | — | EP | disclosed |