Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | HPGD | P15428 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.36 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
| ▸ | CACNG8 | Q8WXS5 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | ERN1 | O75460 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27377882 | 0.89 | GRIA1 (0.48) | HSD17B10PKMKDM4EHPGDALDH1A1 | |
| SCHEMBL27378008 | 0.85 | HSD17B10 (0.44) | HSD17B10PKMKDM4EHPGDALDH1A1 | |
| SCHEMBL27380409 | 0.85 | HSD17B10 (0.42) | HSD17B10PKMKDM4EHPGDALDH1A1 | |
| SCHEMBL27192346 | 0.85 | KDM4E (0.46) | KDM4ETP53HTTNPEPPSGRIA1 | |
| SCHEMBL27379932 | 0.84 | HSD17B10 (0.45) | HSD17B10PKMKDM4EHPGDALDH1A1 | |
| SCHEMBL27191759 | 0.84 | PTGES (0.46) | KDM4ETP53HTTNPEPPSGAA | |
| SCHEMBL27380562 | 0.83 | HPGD (0.46) | HSD17B10PKMKDM4EHPGDALDH1A1 | |
| SCHEMBL27378570 | 0.83 | NPEPPS (0.39) | HSD17B10PKMKDM4EHPGDALDH1A1 | |
| SCHEMBL27378372 | 0.82 | HSD17B10 (0.45) | HSD17B10PKMKDM4EHPGDALDH1A1 | |
| SCHEMBL27192042 | 0.82 | HSD17B10 (0.48) | HSD17B10PKMKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024031089-A1 | SARS-COV2 MAIN PROTEASE INHIBITORS | GILEAD SCIENCES, INC. (US) | 2024-02-08 | — | — | WO | disclosed |