Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B1 | P14061 | 7/20 | 0.39 |
| ▸ | HSD17B2 | P37059 | 6/20 | 0.39 |
| ▸ | KLKB1 | P03952 | 2/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.38 |
| ▸ | TMPRSS15 | P98073 | 1/20 | 0.38 |
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 2/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | IKBKB | O14920 | 1/20 | 0.34 |
| ▸ | NQO2 | P16083 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27361121 | 0.84 | PFKFB3 (0.36) | PRSS1PFKFB3F10 | |
| SCHEMBL8703824 | 0.83 | KAT6A (0.46) | F10IKBKB | |
| SCHEMBL27379215 | 0.83 | ERCC5 (0.34) | PRSS1F10HDAC1HDAC6 | |
| SCHEMBL27400468 | 0.80 | KAT6A (0.35) | PRSS1F10HSD11B1 | |
| SCHEMBL27379218 | 0.80 | CYP2A6 (0.34) | PRSS1PFKFB3F10 | |
| SCHEMBL27363614 | 0.80 | TBXA2R (0.35) | F10HSD11B1HDAC1HDAC6HPGDS | |
| SCHEMBL27452727 | 0.78 | KAT6A (0.33) | PRSS1F10HSD11B1 | |
| SCHEMBL8699108 | 0.76 | SERPINE1 (0.39) | PRSS1CNR1HDAC1 | |
| SCHEMBL27380656 | 0.76 | KLKB1 (0.43) | HSD17B1HSD17B2KLKB1PRSS1TMPRSS15 | |
| SCHEMBL27334381 | 0.75 | MAPT (0.44) | HSD11B1HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070173-C | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1158606-A | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-09-03 | — | — | CN | disclosed |