Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PFKFB3 | Q16875 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.36 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | ACLY | P53396 | 1/20 | 0.32 |
| ▸ | BCL2L1 | Q07817 | 3/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 3/20 | 0.32 |
| ▸ | F10 | P00742 | 3/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.32 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.32 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27379218 | 0.85 | CYP2A6 (0.34) | PFKFB3CYP2A6KAT6AACLYBCL2L1 | |
| SCHEMBL27383236 | 0.84 | PLA2G10 (0.30) | PLA2G10 | |
| SCHEMBL27380654 | 0.84 | HSD17B1 (0.39) | PFKFB3F10PRSS1 | |
| SCHEMBL27400468 | 0.83 | KAT6A (0.35) | KAT6ABCL2L1MCL1F10PRSS1 | |
| SCHEMBL8703824 | 0.82 | KAT6A (0.46) | KAT6ABCL2L1MCL1F10F2 | |
| SCHEMBL27379215 | 0.82 | ERCC5 (0.34) | KAT6ABCL2L1MCL1F10PRSS1 | |
| SCHEMBL27452727 | 0.81 | KAT6A (0.33) | KAT6ABCL2L1MCL1F10PRSS1 | |
| SCHEMBL27363614 | 0.79 | TBXA2R (0.35) | KAT6ABCL2L1MCL1F10F2 | |
| SCHEMBL27359862 | 0.78 | SLC9A1 (0.36) | KAT6AF10PRSS1PRSS2PRSS3 | |
| SCHEMBL27359875 | 0.78 | BCAT2 (0.36) | KAT6ALMNAMAPTNPSR1F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070173-C | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 2001-08-29 | — | — | CN | disclosed |
| CN-1158606-A | Benzoylguanidine derivatives as medicaments | FUJISAWA PHARMACEUTICAL CO (JP) | 1997-09-03 | — | — | CN | disclosed |