Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SERPINE1 | P05121 | 2/20 | 0.39 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | ERCC5 | P28715 | 2/20 | 0.35 |
| ▸ | FEN1 | P39748 | 2/20 | 0.35 |
| ▸ | CNR2 | P34972 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | TRIM24 | O15164 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | MMP12 | P39900 | 1/20 | 0.33 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PLG | P00747 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703824 | 0.83 | KAT6A (0.46) | ERCC5FEN1F2PLGPLAU | |
| SCHEMBL27452727 | 0.80 | KAT6A (0.33) | ERCC5FEN1PRSS1PRSS2PRSS3 | |
| SCHEMBL27379215 | 0.78 | ERCC5 (0.34) | HDAC2ERCC5FEN1HDAC1CA12 | |
| SCHEMBL8700435 | 0.77 | KAT6A (0.32) | PRSS1PRSS2PRSS3 | |
| SCHEMBL27476255 | 0.77 | KAT6A (0.33) | PRSS1PRSS2PRSS3F2 | |
| SCHEMBL27334381 | 0.76 | MAPT (0.44) | ERCC5FEN1HDAC1CA12CA1 | |
| SCHEMBL8700259 | 0.76 | L3MBTL1 (0.46) | CA1CA2CA9F2 | |
| SCHEMBL27380654 | 0.76 | HSD17B1 (0.39) | CNR1HDAC1PRSS1 | |
| SCHEMBL27383233 | 0.76 | F10 (0.34) | ERCC5FEN1CA12CA1CA2 | |
| SCHEMBL8705533 | 0.76 | AOC2 (0.51) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5824691-A | CARDIOVASCULAR, CEREBROVASCULAR, RENAL DISEASES; SHOCK, ARTERIOSCLEROSIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-10-20 | — | — | US | disclosed |