Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 1/20 | 0.51 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.49 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 7/20 | 0.41 |
| ▸ | METTL14 | Q9HCE5 | 7/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27382491 | 0.87 | MTNR1A (0.50) | DAOMTNR1AMTNR1BKDM4EALDH1A1 | |
| SCHEMBL27384519 | 0.86 | DAO (0.49) | DAOMTNR1AMTNR1BKDM4ESMN1; SMN2 | |
| SCHEMBL27383634 | 0.83 | DAO (0.46) | DAOSMN1; SMN2METTL3METTL14RAB9A | |
| SCHEMBL27383806 | 0.82 | DAO (0.45) | DAOSMN1; SMN2METTL3METTL14 | |
| SCHEMBL27384259 | 0.80 | KMT2A (0.48) | DAOKDM4EALDH1A1MAPTMETTL3 | |
| SCHEMBL13415981 | 0.79 | MTNR1A (0.73) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL27382672 | 0.77 | HSD17B10 (0.48) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL27382489 | 0.76 | SMN1; SMN2 (0.47) | MTNR1AMTNR1BKDM4EALDH1A1MAPT | |
| SCHEMBL3031466 | 0.74 | KDM4E (0.55) | DAOKDM4EALDH1A1MAPTHSD17B10 | |
| SCHEMBL18361830 | 0.72 | KDM4E (0.52) | DAOMTNR1AMTNR1BKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |