Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.44 |
| ▸ | DAO | P14920 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | METTL3 | Q86U44 | 9/20 | 0.42 |
| ▸ | METTL14 | Q9HCE5 | 9/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.40 |
| ▸ | TPSD1 | Q9BZJ3 | 1/20 | 0.40 |
| ▸ | TPSG1 | Q9NRR2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384257 | 0.84 | RAB9A (0.50) | KMT2ARAB9ANPC1MAPK1MEN1 | |
| SCHEMBL27384644 | 0.83 | MAPK1 (0.46) | KMT2ARAB9ANPC1MAPK1METTL3 | |
| SCHEMBL27247001 | 0.81 | MTNR1A (0.56) | KMT2ARAB9ANPC1MEN1KDM4E | |
| SCHEMBL27382485 | 0.80 | DAO (0.51) | KMT2ARAB9ADAOMETTL3METTL14 | |
| SCHEMBL27384640 | 0.79 | MAPK1 (0.46) | KMT2ARAB9ANPC1MAPK1TPSAB1 | |
| SCHEMBL27384652 | 0.79 | SMN1; SMN2 (0.41) | RAB9AMAPK1 | |
| SCHEMBL27382491 | 0.79 | MTNR1A (0.50) | DAOMETTL3METTL14KDM4EALDH1A1 | |
| SCHEMBL27384519 | 0.78 | DAO (0.49) | RAB9ADAOMETTL3METTL14KDM4E | |
| SCHEMBL27383634 | 0.77 | DAO (0.46) | RAB9ADAOMETTL3METTL14 | |
| SCHEMBL27383806 | 0.76 | DAO (0.45) | DAOMETTL3METTL14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |