Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23034228 | 0.93 | SIGMAR1 (0.37) | SIGMAR1ALDH1A1TSHRL3MBTL1ACHE | |
| SCHEMBL3309160 | 0.80 | LMNA (0.39) | — | |
| SCHEMBL3311908 | 0.78 | LMNA (0.38) | L3MBTL1MAPK1 | |
| Bromide SCHEMBL2354969 | 0.78 | LMNA (0.38) | — | |
| Bromide SCHEMBL2354546 | 0.77 | LMNA (0.36) | — | |
| SCHEMBL7703213 | 0.74 | MEN1 (0.36) | SIGMAR1ALDH1A1ACHEMEN1KMT2A | |
| SCHEMBL16376637 | 0.74 | MEN1 (0.36) | SIGMAR1ALDH1A1ACHEMEN1KMT2A | |
| SCHEMBL23652517 | 0.73 | LMNA (0.30) | — | |
| SCHEMBL21243176 | 0.71 | — | — | |
| SCHEMBL25090262 | 0.71 | MEN1 (0.34) | SIGMAR1ALDH1A1ACHEMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024102621-A1 | AKT1 MODULATORS | ALTEROME THERAPEUTICS, INC. (US) | 2024-05-16 | — | — | WO | disclosed |