Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 12/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.37 |
| ▸ | CYP2J2 | P51589 | 3/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27384658 | 0.90 | HTT (0.46) | SMN1; SMN2MAPK1EPHX2HRH3HTT | |
| SCHEMBL27384356 | 0.86 | SMN1; SMN2 (0.40) | SMN1; SMN2MAPK1EPHX2RAB9ACYP2C9 | |
| SCHEMBL27384661 | 0.85 | EPHX2 (0.39) | SMN1; SMN2EPHX2RAB9ACYP2C9CYP2J2 | |
| SCHEMBL27384649 | 0.85 | HTT (0.42) | SMN1; SMN2MAPK1EPHX2RAB9ACYP2C9 | |
| SCHEMBL27384854 | 0.84 | MAPK1 (0.41) | SMN1; SMN2MAPK1EPHX2RAB9AGRIN2B | |
| SCHEMBL27382489 | 0.81 | SMN1; SMN2 (0.47) | SMN1; SMN2RAB9AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL27382554 | 0.80 | MTNR1A (0.46) | SMN1; SMN2MAPK1RAB9ACYP2C9GRIN2D | |
| SCHEMBL30946075 | 0.80 | MAPK1 (0.34) | SMN1; SMN2MAPK1EPHX2CYP2C9CYP2J2 | |
| SCHEMBL30946079 | 0.80 | EPHX2 (0.35) | MAPK1EPHX2CYP2C9CYP2J2GRIN2B | |
| SCHEMBL27383138 | 0.79 | SMN1; SMN2 (0.45) | SMN1; SMN2MAPK1RAB9AGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024081748-A2 | INHIBITORS OF SOLUTE CARRIER FAMILY 6A MEMBER 19 (SLC6A19) AND METHODS OF USE THEREOF | MAZE THERAPEUTICS, INC. (US) | 2024-04-18 | — | — | WO | disclosed |