Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LDHA | P00338 | 2/20 | 0.32 |
| ▸ | LDHB | P07195 | 2/20 | 0.32 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | BRS3 | P32247 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRM1 | Q13255 | 1/20 | 0.31 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27385298 | 0.80 | LDHA (0.32) | LDHALDHB | |
| SCHEMBL27491925 | 0.79 | P2RY1 (0.33) | — | |
| SCHEMBL27475100 | 0.79 | LDHA (0.44) | LDHALDHBALDH1A1KDM4EGAA | |
| SCHEMBL27483104 | 0.79 | L3MBTL1 (0.35) | ALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL27481644 | 0.79 | KDM4E (0.32) | LDHALDHBALDH1A1KDM4EGAA | |
| SCHEMBL27447625 | 0.76 | GRIN2D (0.39) | ALDH1A1BRS3MAPK1GRIN2DGRIN2A | |
| SCHEMBL27490519 | 0.75 | KDM4E (0.43) | ALDH1A1BRS3KDM4EHSD17B10MAPK1 | |
| SCHEMBL8462262 | 0.75 | KDM4E (0.45) | THRBALDH1A1BRS3KDM4EGAA | |
| SCHEMBL27483105 | 0.74 | LDHA (0.42) | LDHALDHBALDH1A1GAA | |
| SCHEMBL6046232 | 0.74 | KDM4E (0.40) | ALDH1A1BRS3KDM4EGAAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1068318-C | 2-substituted 1,2, 5-thiadiazolidin-3-one 1, 1-dioxides and compositions and methods of use thereof | SANOFI SYNTHELABO (FR) | 2001-07-11 | — | — | CN | disclosed |
| CN-1173176-A | 2 -substituted 1, 2, 5 -thiadiazolidin-3 -one 1, 1-dioxides and compositions and method of use thereof | SANOFI WINTHROP INC (US) | 1998-02-11 | — | — | CN | disclosed |
| CN-1173175-A | Substituted 2-arylcarbonyloxymethyl-1, 2, 5-thiadiazolidin-3-one 1, 1-dioxide derivatives and compositions and methods of use thereof | SANOFI WINTHROP INC (US) | 1998-02-11 | — | — | CN | disclosed |
| CN-1173130-A | 2 -heterocyclyloxy and thiomethyl -1, 2, 5 -thiadiazolidin -3 -one 1, 1 -dioxides and compositions and method of use thereof | SANOFI WINTHROP INC (US) | 1998-02-11 | — | — | CN | disclosed |
| CN-1173179-A | Substituted 2 -(phosphinyloxymethyl) -1, 2, 5 -thiadiazolidin -3 -one 1, 1 -dioxides and compositions and method of use thereof | SANOFI WINTHROP INC (US) | 1998-02-11 | — | — | CN | disclosed |