Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2529176 | 0.84 | ALDH1A1 (0.48) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL21806003 | 0.84 | ABCB1 (0.45) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL2529177 | 0.84 | ALDH1A1 (0.48) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL24027253 | 0.84 | ABCB1 (0.45) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL5859962 | 0.83 | USP2 (0.43) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL25237873 | 0.82 | USP2 (0.47) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL25582849 | 0.80 | ALDH1A1 (0.40) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL18852406 | 0.79 | PIK3CD (0.58) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL2323290 | 0.79 | USP2 (0.50) | USP2SMN1; SMN2ALDH1A1ABCB1HTT | |
| SCHEMBL29223471 | 0.79 | USP2 (0.50) | USP2SMN1; SMN2ALDH1A1ABCB1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1072661-C | Novel substituted [2-(1-piperazinyl) ethoxy] methyl | UCB SA (BE) | 2001-10-10 | — | — | CN | claimed |
| CN-1215395-A | Novel substituted [2-(1-piperazinyl) ethoxy] methyl | UCB SA (BE) | 1999-04-28 | — | — | CN | claimed |
| CN-1072661-C | Novel substituted [2-(1-piperazinyl) ethoxy] methyl | UCB SA (BE) | 2001-10-10 | — | — | CN | disclosed |
| CN-1215395-A | Novel substituted [2-(1-piperazinyl) ethoxy] methyl | UCB SA (BE) | 1999-04-28 | — | — | CN | disclosed |