SCHEMBL27385459

SCHEMBL27385459

C=CC(=O)NN1CNCNC1

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
ALDH1A1 P00352 1/20 0.33
MAPK1 P28482 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
F13A1 P00488 1/20 0.33
TGM2 P21980 1/20 0.33
TGM1 P22735 1/20 0.33
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3806131 0.80 TGM2 (0.40) TSHRALDH1A1MAPK1TDP1F13A1
SCHEMBL3753325 0.75 TGM2 (0.45) TSHRALDH1A1MAPK1TDP1F13A1
SCHEMBL907519 0.75 TSHR (0.40) TSHRALDH1A1MAPK1TDP1F13A1
SCHEMBL28988331 0.75
SCHEMBL4120737 0.75 TSHR (0.40) TSHRALDH1A1MAPK1TDP1F13A1
SCHEMBL1337362 0.71 TGM2 (0.42) TSHRALDH1A1MAPK1TDP1F13A1
SCHEMBL26690315 0.71
SCHEMBL27091885 0.70 TSHR (0.38) TSHRALDH1A1MAPK1TDP1F13A1
SCHEMBL615220 0.70 HTT (0.41) TSHRALDH1A1MAPK1TDP1F13A1
SCHEMBL1282936 0.69

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1076419-C Fiber treatment method TANSEL CO LTD (GB) 2001-12-19 CN claimed
CN-1146223-A Fiber treatment method COURTAULDS FIBRES HOLDINGS LTD (GB) 1997-03-26 CN claimed
CN-115627632-A Lyocell staple fiber and preparation method thereof 中国纺织科学研究院有限公司 2023-01-20 CN disclosed
CN-103306136-A Cross-linking agent composition, antigen fibrillating solution spinning cellulose fiber, and preparation methods thereof CHINA TEXTILE ACADEMY 2013-09-18 CN disclosed
CN-1076419-C Fiber treatment method TANSEL CO LTD (GB) 2001-12-19 CN disclosed
CN-1146223-A Fiber treatment method COURTAULDS FIBRES HOLDINGS LTD (GB) 1997-03-26 CN disclosed